Our 3 step process provides affordable, convenient, and accurate testing in the comfort of your home
Get health tests delivered to your doorstep with just a few clicks.
Complete your MTHFR test at home right from your comfy couch, and mail it to our lab with a prepaid shipping label (Monday-Friday).
Receive your test results in 5-6 business days & get the clarity you deserve, confidentially.
The MTHFR gene helps folate work or methylate in your body. It also plays a role in making mood neurotransmitters like serotonin, dopamine, and others. These neurotransmitters are critical for mental health and regulating your mood.
We test for the 677 and the 1298 variants. The majority of research has focused on the 677 variants, but new emerging studies are beginning to look deeper into the 1298 variants. Depressed mood, depression disorder, and major depression disorder have been associated with the 677 variants of the MTHFR gene.
The MTHFR gene helps regulate an amino acid called homocysteine. High levels can damage blood vessels when elevated and increase your risk for blood clots.
The empowerDX MTHFR Gene Test is the preferred at-home test by the American Pregnancy Association (APA). MTHFR affects folic acid metabolism, which is critical for a healthy pregnancy.
Find out today if you have a variant of this methylation gene.
MTHFR gene variants are associated with depressed mood, anxious feelings and fertility issues
In the context of the MTHFR gene, methylation is the activation of certain B vitamins in your body. If you have a genetic variant, previously called a genetic mutation, then your body may be less effective at methylating or activating folate (vitamin B9), B6 (pyridoxine), and B12 (cobalamin). Genetic methylation issues are linked to depressed mood, pregnancy health concerns, and headaches.
Your order will be delivered with FedEx Ground within 5 business days. At home tests are shipped Monday – Friday. Make sure to order in advance to avoid possible shipping delays.
Collect your sample with a simple & painless mouth swab on the inside of your cheek. All from the comfort of your home.
Yes! This test requires thirty minutes of fasting. Do not eat, smoke, or drink caffeinated beverages 30 minutes before collection.
You should plan to ship your sample back the same day you collect it. Take your completed kit to a local FedEx drop box before end-of-day pickup to have it overnighted to the lab (Monday – Friday only). FedEx drop boxes do NOT pick up on Saturday or Sunday. empowerDX is not responsible for FedEx shipping delays.
Your at-home MTHFR test results will be available within 5-6 business days of the lab receiving your completed kit. You’ll get an email the moment your results are ready in our secure online portal. View, download and print them anytime, and feel free to share them with your healthcare provider.
Absolutely. If you order a kit for someone else, the person who is collecting the sample must create a profile to match the name and date of birth on the collection tube.
PLEASE NOTE: Our genetic tests will be run only ONE TIME per person. If you activate more than one kit under your name, your sample is only processed once.
Absolutely. The person receiving the gifted kit must use the blank label within the kit when collecting their sample.
A separate account is required for each family member activating a kit. The sample tube must have the name, date of birth, and date of collection of the family member or child using the kit. This name label must match the account profile when the kit is activated or results will NOT be offered.
If the 2 letters on your lab report match, then the result is homozygous (e.g. C/C or T/T or A/A). If the 2 letters do NOT match, then the result is heterozygous (e.g. C/T or A/C). There are two SNPs of this gene reported (677 and 1298), so each gene can be heterozygous or homozygous.
MTHFR 677
MTHFR 1298
empowerDX lab results are intended for informational and educational purposes only, with the exception of infectious disease testing which is diagnostic. Information from empowerDX is not meant to serve as treatment advice or treatment recommendation for any health condition. We strongly recommend you review lab results with your physician.
The cost of shipping is included in the price. There's no additional charge for shipping your test to your home or office. Every test kit comes with a prepaid return shipping label that should be used to ship the kit back to our laboratories for analysis and reporting. All tests are shipped to you with FedEx Ground unless otherwise specified.
For more shipping information, please visit our Terms of Service page.
Yes, the American Pregnancy Association (APA) has formally endorsed the empowerDX MTHFR Gene Test for testing at home.
APOE is strongly linked to Alzheimer's disease. Celiac HLA genes can rule out celiac disease with >99% certainty. Factor V and prothrombin may be increasing your risk for blood clots. Find out answers with an easy mouth swab.
Test your MTHFR gene along with 10 other factors that can affect your ability to mentally thrive. Uncover imbalances in your sex hormones, thyroid levels, nutrients and an antibody level.
Read physician-reviewed articles that link MTHFR variants to mood issues
"...this was an easy swab. Shipping was quick...there was a clear user interface to see my results. Would recommend the empowerDX MTHFR test to anyone!"
- Erika
"...this was an easy swab. Shipping was quick...there was a clear user interface to see my results. Would recommend the empowerDX MTHFR test to anyone!"
- Erika
We send accurate health tests to your door so you can get tested in the comfort of your home.
Get faster, accurate results from real labs and real experts, and get the best care possible right from home.
Your health is your business – so our online portal delivers secure test results.
Get tested on your schedule, and use our step-by-step guide to collect your sample.
All tests are eligible for HSA and FSA purchasing.
We use the latest technologies to provide you with the health information you need.
Explore volume pricing on the MTHFR Gene Test
A test guide to better understand the MTHFR results.
Accurate results for the 677 and 1298 gene markers.
Secure online portal access from any device at every location.
Available for volume orders and distribution in all 50 states.
With a quick & easy mouth swab from home
