Celiac Risk Gene Test (HLA)$199

What does it take to develop celiac disease?

HLA genes, gluten and a trigger must all be present

 
What is celiac disease?

Celiac disease is an autoimmune disease in which the body’s immune system attacks the small intestine when gluten is consumed. The damaged small intestine loses its ability to properly absorb nutrients. Celiac disease can develop at any age after gluten consumption begins. If left untreated, celiac disease can lead to serious health complications including: anemia, autoimmune disorders, coronary artery disease, epilepsy, intestinal cancers, migraines, miscarriage, osteoporosis, rash (dermatitis herpetiformis), and short stature. Currently, a lifelong adherence to a strict gluten-free diet is the only treatment for this condition. In order to develop this disease, three things are needed: (1) your celiac HLA genes are "positive" for celiac disease risk (2) you eat gluten-containing foods like wheat or barley (3) the disease is activated by an environmental trigger

 
1. Inherited HLA genes
 
2. Eating gluten
 
3. Disease activation
 
Recovery

Celiac disease is an autoimmune disease in which the body’s immune system attacks the small intestine when gluten is consumed. The damaged small intestine loses its ability to properly absorb nutrients. Celiac disease can develop at any age after gluten consumption begins. If left untreated, celiac disease can lead to serious health complications including: anemia, autoimmune disorders, coronary artery disease, epilepsy, intestinal cancers, migraines, miscarriage, osteoporosis, rash (dermatitis herpetiformis), and short stature. Currently, a lifelong adherence to a strict gluten-free diet is the only treatment for this condition. In order to develop this disease, three things are needed: (1) your celiac HLA genes are "positive" for celiac disease risk (2) you eat gluten-containing foods like wheat or barley (3) the disease is activated by an environmental trigger

Take this test if you have...

Fatigue or low energy levels regularly
Mental health issues like depressed mood, anxious feelings or irritability
Brain fog, trouble focusing or concentrating with everyday tasks
Gut problems like bloating, gas, constipation, diarrhea or acid reflux
Migraines or chronic headaches without a known cause
Family history of celiac disease or gluten sensitivity
A gluten-free diet and want to rule out celiac disease
Been diagnosed with IBS and want to make sure you don't have celiac
Symptoms when you eat wheat, barley, rye or any form of gluten
To be 99% sure it's not celiac disease after a negative antibody test (tTG-IgA)

How it works

Our 3 step process provides affordable, convenient, and highly accurate genetic testing in the comfort of your home

1

Order online

Get health tests delivered to your doorstep with just a few clicks.

2

Collect at home

Complete your test right from your comfy couch, and mail it to our lab with a prepaid shipping label (Monday-Friday).

3

Get secure results

Receive your celiac test results in 10 business days & get the clarity you deserve, confidentially.

The path to a celiac diagnosis

If your HLA markers are negative for celiac risk, then it's very unlikely for you to develop celiac disease. HLA stands for human leukocyte antigen. HLA's are encoded by highly complex genes that tell parts of your immune system how to function properly. HLA gene testing is difficult to access and is not part of standard DNA testing. Celiac disease is a genetic autoimmune disease that occurs when HLA factors lead to an immune response that damages the lining of the small intestine when exposed to gluten and activated by certain environmental triggers. Our test identifies this genetic predisposition to HLA factors that are necessary for the development of celiac disease.

The details

Get to know the celiac risk HLA gene test

Why test?
Easy collection
Secure results
Test guide
Lab expertise
Methodology

Our Celiac Risk Gene Test will not diagnose celiac disease. However, it will reveal if you could develop celiac disease in your lifetime. A negative test is a powerful tool to rule out celiac disease and consider other causes of symptoms.

How do you get celiac disease? Explore this chart to find out.

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Who is empowerDX?

Your trusted source for easy at-home health testing

Questions?

Is empowerDX sponsoring the Celiac Disease Foundation?

empowerDX is a proud sponsor of the nonprofit organization Celiac Disease Foundation (celiac.org).

The Foundation is leading the way in accelerating celiac disease research, raising international awareness for this under-diagnosed disease, and providing educational and nutritional resources for those living with or caring for those with celiac disease at celiac.org. Their mobile app “Eat! Gluten-Free” provides detailed meal plans, gluten-free product recommendations, and healthy recipes to empower people with celiac disease to thrive.

When will my kit be delivered?

Your order will be delivered with FedEx Ground within 5 business days. At home tests are shipped Monday – Friday. Make sure to order in advance to avoid possible shipping delays.

How do I collect my sample?

Collect your sample with a simple & painless mouth swab on the inside of your cheek. All from the comfort of your home.

Does this test require fasting?

Yes! This test requires thirty minutes of fasting. Do not eat, smoke, or drink caffeinated beverages 30 minutes before collection.

How long does my sample last after collection?

You should plan to ship your sample back the same day you collect it. Take your completed kit to a local FedEx drop box before end-of-day pickup to have it overnighted to the lab (Monday – Friday only). FedEx drop boxes do NOT pick up on Saturday or Sunday. empowerDX is not responsible for FedEx shipping delays.

When will I receive my result?

Your at-home Celiac Risk Gene Test results will be available within 10 business days of the lab receiving your completed kit. You’ll get an email the moment your results are ready in our secure online portal. View, download and print them anytime. Feel free to share them with your healthcare provider.

Can I order more than one kit?

You are welcome to order more than one kit! If you order a kit for someone else, the person who is collecting the sample must create a profile and match their name and date of birth on the collection tube.

PLEASE NOTE: Our genetic tests will be run only ONE TIME per person. If you activate more than one kit under your name, your sample is only processed once.

Can I purchase a kit for someone else?

Absolutely. The person receiving the gifted kit must use the blank label within the kit when collecting their sample and create a profile for activation.

How do I activate a kit for my family member or child?

A separate account is required for each family member activating a kit. The sample tube must have the name, date of birth, and date of collection of the family member or child using the kit. This name label must match the account profile when the kit is activated or results will NOT be offered.

Do I have to eat gluten to get an accurate result?

No! This test will see if you have HLA-DQ2, HLA-DQ8, and DQA1*05. These are the 3 HLA gene markers that determine if have the potential to get celiac in your lifetime. They will not change or vary based on your intake of gluten.

If I receive a positive result, does that mean I have celiac disease?

No, this is not a diagnostic test. Many people have a positive result and never get celiac disease. A positive result is necessary to develop celiac disease – it means you could have celiac disease now or develop it in your lifetime. If you have symptoms of celiac disease and a positive test result, it is important to work with a healthcare provider to determine your diagnosis.

If I receive a negative result, does that mean I do not have celiac disease?

If your HLA markers are negative, then it's very unlikely for you to develop celiac disease. Negative results rule out celiac disease with 99% confidence.

Is this celiac HLA gene test the same as a celiac IgA antibody test?

No, these are different tests. Our HLA celiac risk gene test assesses whether you have risk of current celiac disease or developing it in your lifetime. A tTG-IgA antibody test for celiac disease is a screening blood test with limitations that are important to understand. Biopsy during an endoscopy exam remain the gold standard for celiac disease diagnosis.

Important information about my lab results

empowerDX lab results are intended for informational and educational purposes only, with the exception of infectious disease testing which is diagnostic. Information from empowerDX is not meant to serve as treatment advice or treatment recommendation for any health condition. We strongly recommend you review lab results with your physician.

Shipping info

The cost of shipping is included in the price. There's no additional charge for shipping your test to your home or office. Every test kit comes with a prepaid return shipping label that should be used to ship the kit back to our laboratories for analysis and reporting. All tests are shipped to you with FedEx Ground unless otherwise specified.

For more shipping information, please visit our Terms of Service page.

Free health quiz

Not sure what test you need? Take our brief health quiz to find out.

Unravel more about your genes and nutrients

MTHFR variants are associated with mental health issues, and APOE is strongly linked to Alzheimer's disease. Gut health problems can increase your risk for low vitamin B12 and low folate levels.

Why empowerDX?

At home testing

We send accurate health tests to your door so you can get tested in the comfort of your home.

CLIA-certified laboratories

Get faster, accurate results from real labs and real experts, and get the best care possible right from home.

Secure results

Your health is your business – so our online portal delivers secure test results.

Convenient and easy collection

Get tested on your schedule, and use our step-by-step guide to collect your sample.

Eligible for HSA/FSA

All tests are eligible for HSA and FSA purchasing.

Cutting edge and evidence-based

We use the latest technologies to provide you with the health information you need.

Get celiac testing for your organization

The empowerDX Celiac Risk Gene Test is available in shipments of 10+ kits

What you get

Click here for volume pricing on the Celiac Risk Gene Test.

A test guide to better understand the celiac results.

Accurate results including a "negative" or "positive" for all 3 markers.

Secure online portal access from any device at every location.

A 30 min telemedicine consult with a clinician for an additional $99.